Liposome encapsulated daunorubicin (daunoxome) for acute leukemia.
نویسندگان
چکیده
Haematologica vol. 85(3):March 2000 7. Dunphy CH, Gregowicz AJ, Rodriguez G Jr. Natural killer cell acute leukemia with myeloid antigen expression. A previously undescribed form of acute leukemia. Am J Clin Pathol 1995; 104:212-5. 8. Nagata T, Higashigawa M, Nagai M, et al. A child case of CD34+, CD33-, HLA-DR-, CD7+, CD56+ stem cell leukemia with thymic involvement. Leuk Res 1996; 20:983-5. 9. Suzuki R, Yamamoto K, Seto M, et al. CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia: a distinct hematolymphoid disease entity. Blood 1997; 90:2417-28. 10. Di Giuseppe JA, Louie DC, Williams JE, et al. Blastic natural killer cell leukemia/lymphoma: a clinicopathologic study. Am J Surg Pathol 1997; 21:1223-30.
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1. Forssen EA, Ross ME. Daunoxome treatment of solid tumors: preclinical and clinical investigations. J Liposome Res 1994; 4:481-512. 2. Money-Kyrle JE, Bates E, Ready J, Gazzard BG, Phillips RH, Boag FC. Liposomal daunorubicin in advanced Kaposi’s sarcoma: a phase II study. Clin Oncol 1993; 5:367-371. 3. Michieli M, Damiani D, Ermacora A, Masolini P, Michelutti A, Baccarani M. Liposome encapsu...
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Elderly acute lymphoblastic leukemia (ALL) is a rare condition associated with low complete remission (CR) rate and short survival. In order to improve these results, we evaluate the efficacy and toxicity of Daunoxome, a liposomal daunorubicin, exhibiting toxicity profile and pharmacokinetic indices better than standard daunorubicin. In total, 15 consecutive patients with nonmature ALL were enr...
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Anthracycline compounds including daunorubicin are the foundation of many modem chemotherapeutic regimens. However, the side-effects of these compounds can be severe, leading to alopecia, nausea, immune deficiency, and cardiotoxicity. For immunocompromised patients with aggressive Kaposi's sarcoma (KS), these complications often preclude the completion of appropriate chemotherapeutic regimens. ...
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ورودعنوان ژورنال:
- Haematologica
دوره 85 3 شماره
صفحات -
تاریخ انتشار 2000